The Cronkhite-Canada syndrome
نویسندگان
چکیده
The eighteenth patient and seventh survivor with the Cronkhite-Canada syndrome is described. A remission of 9 years followed gastrectomy and steroid therapy. Findings on seventeen other patients described in the literature are reviewed. The histological features are discussed in detail. The jejunum, though macroscopically normal, showed oedema, increased vascularity and mucous gland secreting activity. The possible importance of this increased vascularity in the aetiology of this syndrome is discussed.
منابع مشابه
Cronkhite-Canada syndrome.
Cronkhite-Canada syndrome is one of the rare causes of multiple polyposis, characterised by generalised gastrointestinal polyposis, cutaneous hyperpigmentation, alopecia, and nail dystrophy.' Although Cronkhite and Canada described it for the first time in 1955, little is known about its aetiology and the prognosis remains poor. We describe a case of CronkhiteCanada syndrome in a 79-year-old Ja...
متن کاملCronkhite-Canada syndrome complicated with multiple gastric cancers and multiple colon adenomas
BACKGROUND We experienced a case in which Cronkhite-Canada Syndrome presented with complications of multiple gastric cancers and multiple colon adenomas. CASE REPORT Our case is a 64-year-old male who visited a nearby hospital with diarrhea and weight loss. The patient was anemic and hypoproteinemic, with multiple polyps in the stomach, duodenum, and large intestine. He also presented with al...
متن کاملProctocolectomy for persistent haematochezia in a patient with Cronkhite-Canada Syndrome
Cronkhite-Canada syndrome is an extremely rare condition of gastrointestinal polyposis in which the main presenting features are diarrhoea and dysgeusia. The polyps in this condition are characteristically distributed throughout the entire gastrointestinal tract except the oesophagus, and these patients exhibit unique ectodermal abnormalities. Herein, we report a 50-year-old male who had recurr...
متن کاملCronkhite-Canada syndrome presenting as eosinophilic gastroenteritis.
Cronkhite-Canada syndrome (CCS), first described in 1955, is a rare clinical syndrome of unknown etiology. CCS is diagnosed clinically, and the presenting symptoms include alopecia, cutaneous hyperpigmentation, gastrointestinal polyposis, and onychodystrophy, often accompanied by diarrhea, weight loss, and abdominal pain. We describe a unique case of CCS that presented with eosinophilic infiltr...
متن کاملSirolimus in Refractory Cronkhite-Canada Syndrome and Focus on Standard Treatment
Cronkhite-Canada syndrome is a rare syndrome consisting of extensive gastrointestinal polyposis and ectodermal changes including cutaneous hyperpigmentation, alopecia, and onychodystrophy. We report the case of a 45-year-old Caucasian male patient who failed multiple treatments over 2 years including steroids, azathioprine, adalimumab, and cyclosporine. He had recurrent and prolonged hospitaliz...
متن کاملPolyps! Polyps! And More Polyps! - The First Case of Cronkhite-Canada Syndrome in Malaysia.
Cronkhite-Canada Syndrome (CCS) is a syndrome characterised by a constellation of signs including but not limited to onychodystrophy of the finger and toe nails, skin hyperpigmentation and alopecia. Endoscopic features showed hamartomatous polyps involving all segments of the gastrointestinal tract with the characteristic exception of being oesophageal sparring. These polyps show confirmation b...
متن کامل